Colorectal Cancer Treatment Colorectal Cancer Treatment
Once your doctor knows knows you have Colorectal Cancer, the next step is to determine what type of treatment is best for you. The first treatment you get (called "initial therapy") may be different for you than for someone else you know with Colorectal Cancer. Along the way, you may need to have different kinds of treatment, such as surgery, chemotherapy or radiation treatments. There are many treatment options available, and you should discuss each of them with your doctor.

Colorectal Cancer Treatment Options 1:

Surgery
Surgery may be performed at all stages of Colorectal Cancer. In early stages, the gastroenterologist may be able to remove the cancer without cutting into the abdomen (above your waist). This is called a local excision. The doctor performs the minor surgery through a slender tube inserted through the rectum and into the colon. If a polyp is found and removed, it is called a polypectomy. Removing a polyp early on-before cancer cells appear-may prevent cancer from ever developing.

If a large tumor is found, the surgeon will remove the cancer and a small amount of normal, healthy tissue around it. This is called bowel or colon resection. The healthy parts of the colon are reattached. A colon resection rarely causes major digestive problems.

If the colon cannot be reattached, an opening called a stoma will be made on the outside of the body. This allows waste that can no longer travel through the colon to pass out of the body. This is called a colostomy. Sometimes a colostomy is only needed until the colon has healed and can be reconnected. A colostomy can have a major impact on lifestyle, but sometimes it is the only option to preserve your health.

Colorectal Cancer Treatment Options 2:

Adjuvant Therapy
The word adjuvant [ADD-joo-vent] means "to help reach a goal." And adjuvant therapy is just that. It's the idea of using chemotherapy, additional radiation, or other treatments to destroy cancer cells after surgery. The goal is to lower the risk of the cancer coming back. That's why adjuvant therapy is sometimes referred to as an "insurance policy."
 
Some patients require adjuvant therapy, while others do not. Only your healthcare team can tell you if it is needed to treat your condition. To learn more about adjuvant therapy, download "The Patient's Guide to Adjuvant Therapy" brochure.

Colorectal Cancer Treatment Options 3:

Chemotherapy
Most people have heard of chemotherapy. It's the use of powerful chemicals to kill cancer cells. Scientists have been working hard to design chemotherapy so that it "targets" only cancer cells. And there have been great improvements over the years. But even the most advanced chemotherapy drugs still affect normal cells as well as cancer cells.

Chemotherapy is a form of "systemic" therapy. That means it enters the blood, travels through the body, and kills cancer cells no matter where they are. Chemotherapy is typically used as a type of adjuvant therapy to treat Colorectal Cancer. It is also used to shrink tumors or relieve symptoms in patients with advanced Colorectal Cancer. This is called palliative chemotherapy, and it is meant to improve a patient's quality of life while they're living with advanced cancer.

There are many options for chemotherapy treatment. Chemotherapies can be given by pill, IV injection, or catheter (a tube hooked directly into a blood vessel). If you need chemotherapy during the course of treatment, it's a good idea to learn about the different ways it can be given. Be sure to find out more about XELODA, an oral chemotherapy that's proven effective in treating certain types of Colorectal Cancer.

Colorectal Cancer Treatment Options 4:

Radiation Therapy
Radiation therapy kills cancer cells by using high-energy rays pointed at the affected area. It prevents cancer cells from continuing to grow and divide. Radiation therapy is also known as "brachytherapy" [BRAY-kee-ther-a-py]. It can be used as an adjuvant therapy to kill cancer cells not seen during surgery. It may also be used to shrink the tumor and ease symptoms of advanced cancer. Radiation therapy is often used along with chemotherapy to treat cancer.

Colorectal Cancer Treatment Options 5:

Biological Therapy
Biological therapy is the use of substances that have an effect on the body's immune system. These are used to repair, stimulate, or increase the body's natural ability to fight infections and cancer.

For more information about treatment options, download the free "A Patient's Guide to Understanding Colorectal Cancer" brochure.
 
Indications:
XELODA is used to treat:
 
Important Safety Information:
WARNING:
XELODA may increase the effect of other medicines used to thin your blood such as warfarin (COUMADIN®). It is very important that your doctor knows if you are taking a blood thinner such as warfarin because XELODA may increase the effect of this medicine and could lead to serious side effects. If you are taking blood thinners and XELODA, your doctor needs to check more often how fast your blood clots and change the dose of the blood thinner, if needed.
 
  • The most common side effects of XELODA are: diarrhea, nausea, vomiting, sores in the mouth and throat (stomatitis), stomach area pain (abdominal pain), upset stomach, constipation, loss of appetite, and too much water loss from the body (dehydration) (These side effects are more common in patients age 80 and older). Other common side effects are hand-and-foot syndrome (palms of the hands or soles of the feet tingle, become numb, painful, swollen or red); rash; dry, itchy or discolored skin; nail problems; hair loss; tiredness; weakness; dizziness; headache; fever; pain (including chest, back, joint and muscle pain); trouble sleeping; and taste problems. Tell your doctor if you have heart problems because you could have more side effects related to your heart.
     
    These side effects may differ when taking XELODA with docetaxel (TAXOTERE). Please consult your doctor for possible side effects that may be caused by taking XELODA with other therapies.
     
    If you are concerned about these or any other side effects while taking XELODA, talk to your doctor.

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  • Do not take XELODA if you are nursing a baby. Tell your doctor if you are nursing. XELODA may pass to the baby in your milk and harm the baby.
     
    Women should not become pregnant while taking XELODA. XELODA may harm your unborn child. Use effective birth control while taking XELODA. Tell your doctor if you become pregnant. Men should use birth control while taking XELODA.
     
    Do not take XELODA if you are allergic to 5-fluorouracil, capecitabine or any of the ingredients in XELODA. Do not take XELODA if you have been told that you lack the enzyme DPD (dihydropyrimidine dehydrogenase).

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  • Stop taking XELODA immediately and contact your doctor right away if you have the side effects listed below or other side effects that concern you. Your doctor can then adjust XELODA to a dose that is right for you or stop your XELODA treatment for a while. This should help to reduce the side effects and stop them from getting worse.
    • - Diarrhea: if you have an additional 4 bowel movements each day beyond what is normal or any diarrhea at night
    • - Vomiting: if you vomit more than once in a 24-hour time period
    • - Nausea: if you lose your appetite, and the amount of food you eat each day is much less than usual
    • - Stomatitis: if you have pain, redness, swelling or sores in your mouth
    • - Hand-and-Foot Syndrome: if you have pain, swelling or redness of your hands or feet that prevents normal activity
    • - Fever or Infection: if you have a temperature of 100.5°F or greater or other signs of infection
Please be sure to talk to your doctor if you have any questions about your condition or treatment.
 
Please see accompanying patient information and complete Prescribing Information.
 
Adriamycin is a trademark of Pharmacia & Upjohn Company.
Coumadin is a registered trademark of Bristol-Myers Squibb Company.
Taxol is a registered trademark of Bristol-Myers Squibb Company.
Taxotere is a registered trademark of Sanofi-Aventis U.S. LLC.
 
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For more information about XELODA, contact your physician or other healthcare professional.